Archive for October, 2008

Hubble telescope working, taking photos again

Thursday, October 30th, 2008

The Hubble Space Telescope is working again, taking stunning cosmic photos after a one-month breakdown.

The Hubble Space Telescope Science Institute in Baltimore said the $10 billion telescope is as good as it was before a shutdown in late September. That glitch scotched plans for spacewalking astronauts to upgrade the telescope this month.

Scientists made two repair attempts, and last week’s effort apparently worked. NASA released a glimmering new Hubble photo showing two ring-shaped galaxies after they collided.

New vaccine shot triggers robust immunity against flu

Thursday, October 30th, 2008

A single flu shot delivered nasally to ferrets triggered 20 times greater immunity than those conferred by two injections of currently approved vaccines, according to a study.

Ferrets were tested because they represent the most relevant flu animal model for humans. ‘Our… intranasal vaccine adjuvant (added to a drug to improve its effectiveness) system represents a paradigm shift in vaccinology,’ said James R. Baker, Jr, founder and chairman of NanoBio-Corp, which developed the vaccine.

It can be used to safely deliver multiple antigen types directly into the lining of nasal mucosa, rich in dendritic cells that present the antigen(s) to the immune system to help produce antibodies.

In the study, ferrets received 7.5, 15 and 45 micrograms of the flud vaccine. All three doses produced antibody responses substantially higher than those triggered by the standard intramuscular vaccine, according to a NanoBio Corporation release.

‘A large, unmet medical need still exists for protecting people from influenza infection, …a vaccine that would protect people in the face of a flu pandemic,’ said Baker.

NanoBio plans to begin a phase-1 clinical study for seasonal influenza in the first half of 2009 and is currently initiating preclinical studies in pandemic flu.

These results were presented at the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, D.C.

Paying attention to detail

Saturday, October 25th, 2008

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Based on your budget and need, you may even opt for thermal labels. The ribbon-less thermal labels make it easier to print labels of your choice. However, you can go for thermal transfer labels that require ribbons but are more cost-effective. Thermal labels use heat to form images on the labels.

While labels help you organize your workspace better, business cards help you make that great first impression. Printable business cards make more sense as you can print as many cards as you need and as and when you need them. These printable business cards are essential and advantageous to not only home-based business but also to small and medium-size businesses.

While professionalism and trust make a business last, it is proper planning that lays its foundation. Invest time and effort in organizing the business properly to reap the optimum benefits.

Black Custom Wheels

Saturday, October 25th, 2008

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Weird dino rewrites the book on birds

Saturday, October 25th, 2008

A tiny, egg-robbing dinosaur that lived more than 150 million years ago could help explain a key phase in the evolution of birds, scientists reported on Wednesday.

In unusual language for a high-brow journal, Chinese palaeontologists admit the wee dino was, frankly, “bizarre”.

The beast was a distant relative of the Tyrannosaurus rex but was no bigger than a kitten. And it was covered in feathers but couldn’t fly.

The creature lived between 152 and 168 million years ago, according to analysis of its fossil, found in Daohugou in Inner Mongolia, northern China.

Dubbed Epidexipteryx hui, the mini-dino was a two-footed predator, known as a therapod, that lived in the Middle to Late Jurassic era between 152 and 168 million years ago.

It probably weighed no more than 164 grammes, or just over five ounces, and fed opportunistically on eggs it found or stole, according to the paper, which appears in the British weekly journal Nature.

E. hui lived shortly before the famous Archaeopteryx, which arrived on the scene around 150 million years ago and is generally considered to be the first bird.

Despite its many dinosaur features, Archaeopteryx is believed to have been capable of powered flight.

Yet one of the many questions about the “early bird” scenario is exactly why dinosaurs evolved feathers.

Did feathers provide warmth, for instance, or a means of flight, enabling a tree-living dino to jump or glide to safety from a perch or to find food?

The Chinese team, led by the fossil-hunter Xing Xu of the Institute of Vertebrate Palaeontology and Palaeoanthropoloy in Beijing, say a clutch of long, ribbon-like feathers on E. hui’s tale points to a different function.

They believe the unusual plumage was “integumentary ornamentation” — a decorative attachment that helped in mating.

Rather like the peacock spreads out his tail fan to lure a female, the dinosaur would show his feathers in courtship to demonstrate his fitness.

E. hui’s name derives from a Greek composite meaning “feather display” and from Yaoming Hu, a Chinese expert in Mesozoic mammals who died in April this year after a long illness, aged only 42.

Excel Training

Friday, October 24th, 2008

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This means that you might want to look into excel 2003 training for your office. This setup will offer you a nice mix of reliability and function for your everyday use. A good training course will have them making graphs by the end of the first week. This is also important just because of the increased familiarity it will garner. Giving them time to train with the program will make it easier to use overall. Having some time with it will do wonders to their overall chances.

If you have the latest in office software packages, then you could go ahead and get excel 2007 training. This software is fairly simple, so not too much has changed. If you are just upgrading from your current 2003 setup, then you should be able to find a good transition course for just this problem.

Microsoft profit up 2 percent, but outlook soft

Friday, October 24th, 2008

Microsoft is still churning out big profits, but its decision to trim its sails shows that even the world’s largest software maker is feeling the effects of the choppy economy.

Microsoft Corp. said Thursday its fiscal first-quarter profit edged up 2 percent, buoyed by corporate customers that renewed licenses for servers and other business programs.

But Microsoft’s guidance for the current quarter was weaker than Wall Street was expecting. Its shares rose then dipped in extended trading as investors digested the news.

“We, like most companies, saw a slowdown at the tail end of the quarter in particular,” Chief Financial Officer Chris Liddell said in an interview. “We’re now taking a more conservative stance on the balance of the year.”

Liddell said the worst hit among Microsoft’s customers in the just-concluded quarter were small- and medium-sized businesses that “perhaps are more affected by the credit squeeze and who perhaps make decisions on a month-by-month basis.”

In a conference call with investors, Liddell said Microsoft will “tailor our business to whatever the economy brings.”

The CFO said Microsoft will trim operating expenses by $400 million to $500 million in the fiscal year by slowing hiring, cutting marketing expenses and spending less on building the massive data centers that prop up its online business.

“Microsoft isn’t known for great spending restraint,” said Edward Jones analyst Andy Miedler in an interview. “It is clear that Microsoft is now watching its expenses very closely, which is important in this challenging economy.”

In the three months that ended Sept. 30, Microsoft’s earnings rose to $4.37 billion, or 48 cents per share, from $4.29 billion, or 45 cents per share in the same period last year.

Sales improved 9 percent to $15.1 billion.

Microsoft beat Wall Street’s expectations on both counts. Analysts, on average, predicted the Redmond, Wash.-based company would earn 47 cents per share on $14.8 billion in sales, according to a Thomson Reuters survey.

The software maker highlighted a 20 percent third-quarter jump in sales of multiyear contracts to businesses, which helped boost revenue for Microsoft’s server software group and the division that makes Office productivity software.

The server group’s profit increased 20 percent to $1.2 billion, while the division responsible for Office software saw earnings jump 23 percent to $3.3 billion.

The Windows division’s profit, on the other hand, slipped 4 percent to $3.3 billion. Microsoft, which recently launched a massive new advertising campaign to trumpet Windows’ virtues, attributed part of the decline to higher marketing expenses.

The company also blamed some of that decrease on the rising popularity of netbooks, a class of small, inexpensive laptops that on the whole aren’t powerful enough to run the souped-up, pricer versions of Windows Vista.

Sid Parakh, an analyst for McAdams Wright Ragen, said Microsoft also drops the price it charges PC makers for installing Windows on laptops that cost so little.

Microsoft also said revenue from PC makers like Dell Inc. and Hewlett-Packard Co. sank 1 percent as those companies bought a smaller percentage of higher-priced “premium” versions of Windows Vista.

Microsoft’s online division widened its loss in the quarter to $480 million from $270 million last year as the company continues to invest heavily in the unit. Liddell said Web advertising revenue improved 15 percent, with search ads bringing in more than graphical “display ads.” That’s much stronger than the 1 percent gain Yahoo Inc. reported this week in its online ad revenue.

Liddell said Microsoft’s outlook for the current quarter was lower than expected because of an across-the-board slowdown, not pain in one particular area. Microsoft expects to earn 51 to 53 cents per share, on sales of $17.3 billion to $17.8 billion.

Analysts were predicting a profit of 55 cents per share on $18 billion in sales.

Shares of Microsoft slipped 21 cents, or almost 1 percent, to $22.11 in after-hours trading. In the regular session they added 79 cents, or 3.7 percent, to end at $22.32.

Spreading contagion brings key equities index below 10,000

Friday, October 24th, 2008

With the contagion of the financial tsunami that began in the US spreading to all parts of the world, jittery investors went into a selling spree once again Thursday sending a key Indian equities index below the psychologically important 10,000 mark.

The markets finished in the red for the second successive day this week after two successive days of gain early this week and three successive days of losses last week.

The rupee too hit its lowest ever value against the dollar Thursday with the Indian central bank, the Reserve Bank of India’s (RBI) reference rate going down to Rs.49.79 to a dollar.

The RBI reference rate is based on 12 noon rates of a few select banks in Mumbai.

At the close of trading, the benchmark 30-share sensitive index (Sensex) of the Bombay Stock Exchange finished at 9,771.70, down 398.20 points or 3.92 percent from its previous close Wednesday at 10,169.90 points.

The Sensex opened very weak at 9,683.41, down 486.49 points or 4.8 percent from its previous close Wednesday, hit a low of 9,681.28 and then recovered enough to get into positive territory on short covering before sliding again to finish in the red.

The broader 50-share S&P CNX Nifty index of the National Stock Exchange (NSE) also opened weak and went below the psychologically important 3,000 mark before recovering somewhat to get into positive territory for a few minutes before falling again to finish at 2943.15, down 122 points or 3.98 percent from its previous close Wednesday at 3065.15 points.

The BSE midcap index finished at 3,378.72, down 111.67 points or 3.20 percent from its previous close Wednesday at 3,490.39 points.

The BSE smallcap index closed at 3,965.70, down 145.99 points or 3.55 percent from its previous close Wednesday at 4,111.69 points.

Despite lower Indian inflation figures and several positive measures announced by the Indian government, central bank and the market regulator over the past few days, continued uncertainty across the globe was affecting sentiment, analysts said.

“Argentina has now joined the list of countries hit by the financial tsunami,” said Jagannadham Thunuguntla, head of the capital markets arm of India’s fourth largest share brokerage firm, the Delhi-based SMC Group.

“After Iceland, Hungary and Pakistan, the emergence of the contagion in Argentina shows that Europe, East Europe, South East Asia and now Latin America too has been affected indicating the depth and width of the problem,” he said.

Overnight the New York Stock Exchange’s key industrial index closed 6.95 percent down while the key index of the Nasdaq - the stock exchange for technology stocks - finished with a 4.77 percent loss.

Asian markets also provided negative cues with the Nikkei index of the Tokyo Stock Exchange down 2.46 percent and the Hong Kong market’s Hang Seng down 4.65 percent.

Except consumer durables and consumer goods all other sectoral indices finished in the red.

The worst hit were metals, automobiles, oil and gas and realty stocks in that order.

Among the stocks that make up the Sensex, Grasim Industries gained the most, 4.74 percent followed by BHEL 2.74 percent, Larsen & Toubro 2.43 percent and HDFC Bank 2.23 percent.

The biggest losers were Tata Steel shedding 14.85 percent followed by Tata Motors 14.57 percent, Hindalco 13.10 percent and Ranbaxy Laboratories 10.94 percent.

As many as 1,908 or 73.50 percent stocks declined, 622 or 23.96 percent scrips advanced and 66 or 2.54 percent stocks remained unchanged.

How some people can generalise past events for future decisions

Friday, October 24th, 2008

A new research has uncovered how some people are good at generalizing from past experience, while others are not.

The study has revealed how the brain can connect discrete but overlapping experiences to provide a rich integrated history that extends far beyond individually experienced events and may help to direct future choices.

Usually, decisions are guided by drawing on past experiences, perhaps by generalizing across discrete events that overlap in content.

But, how such experiences are integrated into a unified representation was unclear, until now.

The researchers believe that such mechanisms involve the hippocampus, a brain structure closely linked with learning and memory. They also speculate the involvement of the midbrain, as its projections modulate activity in the hippocampus. And activity in both regions has been shown to facilitate encoding of individual episodes.

“We hypothesized that generalization stems from integrative encoding that occurs while experiencing events that partially overlap with previously encoded events and that such integrative encoding depends on both the hippocampus and midbrain dopamine regions. Further, we anticipated that greater hippocampal-midbrain engagement during integrative encoding enables rapid behavioral generalization in the future,” said Dr. Daphna Shohamy from the Department of Psychology at Columbia University.

The researchers used functional magnetic resonance imaging to study participants engaged in an associative learning and generalization task.

They found that activity in the hippocampus and midbrain during learning predicted generalization and observed a cooperative interaction between the hippocampus and the midbrain during integrative encoding.

“By forming a thread that connects otherwise separate experiences, integrative encoding permits organisms to generalize across multiple past experience to guide choices in the present,” explained Dr. Shohamy.

She added: “In people who generalize successfully, the brain is constantly building links across separate events, creating an integrated memory of life’s episodes. For others, although the brain may accurately remember each past event, this integration does not occur, so that when confronted with a new situation, they are unable to flexibly apply what they learned in the past.”

The study was published in the latest issue of the journal Neuron.

Patriots move on without safety Harrison

Thursday, October 23rd, 2008

Rodney Harrison would race downfield with the kickoff team in practice, tackle the returner and stir up all kinds of mayhem.

As part of the group that mimics the New England Patriots next opponent on those plays, he showed the physical play and passion that was his hallmark until his latest, and probably last, injury as an NFL player.

“He goes on the scout kickoff team. He runs down there, makes the tackle every play, gets everybody in trouble,” tight end Benjamin Watson said Wednesday. “Everybody’s mad at him, but that’s Rodney.

“That’s just the kind of player he is.”

Or was.

Harrison’s season officially ended Wednesday when the Patriots placed him on injured reserve. Realistically, his career almost certainly ended two days earlier when he tore the quadriceps muscle in his right thigh, an injury that usually takes eight to 10 months to heal.

Harrison turns 36 on Dec. 15. He is in his 15th season, the final year of his contract. And he suffered his fourth serious injury in four years on the final play of the third quarter of Monday night’s 41-7 win over the Denver Broncos.

He wasn’t in the locker room during the 40 minutes reporters had access Wednesday, but his lessons were: work hard and move on.

“He would say the same thing about anybody else (being sidelined). We’re not going to sit here and have a pity party,” 25-year-old cornerback Ellis Hobbs said. “He’s a loyal and dedicated player to the game, and the way he played the game is really how all of us should play it, man, 100 percent all the way.”

Harrison, a two-time Pro Bowler and two-time Super Bowl winner, will be replaced by 2007 first-round draft choice Brandon Meriweather alongside safety James Sanders. The Patriots signed defensive back Antwain Spann to the active roster from the practice squad and added safety Mark Dillard to the practice squad.

“When tragedy falls upon you, we just keep on moving and just realizing that one person doesn’t make this machine,” Hobbs said. “Whoever’s filling that spot, we’re not asking to go out there and make miracles. Just do your job.”

Meriweather, who dropped several potential interceptions last year, already has three this year. The 24-year-old Sanders is in his second season as a starter.

“We’ll have to count on a lot of people to do some of the things that Rodney did,” coach Bill Belichick said. “Rodney had a lot of different roles for us defensively.”

Harrison is the third key Patriot lost for the season. Quarterback Tom Brady suffered a knee injury in the opener, and running back Laurence Maroney went on injured reserve Monday with a shoulder injury.

“Is there a breaking point?” Hobbs said. “Well, if there is, we haven’t found it.”

A few hours after Maroney went on injured reserve, the Patriots played their best game of the season by dominating Denver to improve to 4-2.

Last season, they overcame the adversity of Spygate — the fallout from the season opener when they taped New York Jets coaches’ signals during the game — and went 18-0 before losing the Super Bowl on a last-minute touchdown.

“We just seem to know how to stay focused,” Hobbs said. “We don’t worry about what we can’t control.”

The loss of Harrison had players reflecting on his emotional style of play, leadership ability and the respect he commanded from teammates. He holds the NFL record for defensive backs with 30 1/2 sacks and, with 34 interceptions, is the only player ever to have at least 30 of each.

“I wish I could be more like him on the field, someone that plays with his reckless abandon but still seems to find a way to be in control and make plays. I can’t say enough good things about him,” fullback Heath Evans said.

“This team always finds ways to rally around and finds ways to make plays and win ballgames when no one expects us to. So I’m sure that won’t change. But if you talk about replacing someone like 37 (Harrison), that just doesn’t happen.”

The Patriots practiced Wednesday for Sunday’s home game against the St. Louis Rams, 2-0 since Jim Haslett took over an 0-4 team.

They’ll have to deal with dangerous running back Stephen Jackson and veteran quarterback Marc Bulger without having Harrison on the field.

“He would be the first one to tell you that the train’s going to keep going,” Watson said, “and whoever goes and plays for him is going to play well and he’ll definitely be there cheering for us, and we’ll still be looking up to him.”