Archive for September, 2008

Media Doesn’t Often Mention Pharma Funding on Research

Tuesday, September 30th, 2008

The mainstream media often fail to report when drug company funding is used for studies of medications, a new review found.

What’s more, there’s a tendency among both medical and mainstream reporters to use brand names, rather than generic names, when referring to specific medications.

And both of these factors work to skew public and medical opinion toward commercial interests, according to the review, published in the Oct. 1 issue of the Journal of the American Medical Association.

This, despite newspaper editors’ assertions to the contrary, the study authors found.

“As a doctor, I am increasingly worried in recent years that company-funded research can’t be trusted in the same way that other research can be trusted,” said study author Dr. Michael Hochman, a resident physician at Cambridge Health Alliance in Cambridge, Mass. “[Also], all of us, doctors, patients, journalists, have gotten into a bad habit of referring to medications by their proprietary brand names. At a philosophical level, I think we need to be referring to them by the generic name. We want to keep commercial interests as much out of the doctor-patient relationship as possible.”

“Funding sources should be included in every story where it’s relevant,” added Andrew Holtz, past president of the Association of Health Care Journalists, former CNN medical correspondent and now an independent journalist. But, he also pointed out, the new study itself may be biased because it only included in its analysis stories of at least 200 words.

“Two hundred words is not a very long story and I didn’t see in the study anything about whether there was a correlation between length of article and how thorough the article was in mentioning funding and generic and brand names,” Holtz said. Such stories, he added, may be leaving out other important information as well, including, for instance, the side effects of a particular drug.

Peer-reviewed medical journals earlier engaged in a similar debate and most now require that study authors disclose funding sources.

The authors of the new study analyzed 306 news articles about medication research from U.S. newspaper and online sites, and they also asked 100 editors at the most widely circulated newspapers in the country about their reporting practices. The studies that were analyzed had been published in five prominent medical journals, including the Journal of the American Medical Association and the New England Journal of Medicine.

Forty-two percent of the news articles did not state when drug research had received funding from the pharmaceutical industry. And when they did, it was often buried in the text.

Sixty-seven percent of 277 articles that reported on medications only used the drug’s brand name in at least half of the references to the medication. According to the study authors, up to $9 billion is spent each year in the United States when doctors prescribe brand name drugs although a generic would do just as well.

Yet 88 percent of the responding newspaper editors thought that articles they published often or always mentioned company funding. And 77 percent of the editors thought their stories referred to medications by their generic names.

Three percent of the newspapers had formal, written policies regarding disclosure of company funding, and 2 percent had such policies regarding the use of generic names of drugs.

“News organizations, in my opinion, really should have explicit written policies that they enforce,” Hochman said. “We always need to disclose how a medical study is funded. I’m particularly concerned about commercial studies. We have many examples of how company-led research led us astray.”

Hochman referred specifically to the Vioxx (rofecoxib) scandal; the arthritis drug was withdrawn from the market in 2004 because of concerns that it increased heart risks.

As for preferring generic drug names — many of which are unpronounceable, even for experts — over brand names, Hochman conceded that will be an uphill battle.

“It’s a problem but we’re not going to change it unless we take the hard step of trying to learn generic names,” he said.

How to share wildest sexual fantasies with your partner

Tuesday, September 30th, 2008

When it comes sharing sexual fantasies, even the ‘closest’ couples find it hard to communicate their innermost ‘naughty acts’ to each other. But if you’re one of those who don’t want to miss out on the fun, then here are few tips to get your mind ‘moving’.Not many couples are able to act out their sexual fantasies even if they are pro in the sack. The problem-How to share your wild thoughts? What would your partner think about you? How would he/she react? Will they comply or not?

Such questions and many others flood the minds of many sexually active adults who want to explore their wildest of sexual dreams, reports Fox News.

While sharing lewd, obscene, or sensuous scenes with your partner can pose to be a big problem, it also has an upside- not only can you divulge your sexual desires but could even get a sneak peek into your lover’s libidinous thoughts as well.

So if you want to spice things up by sharing it all, sex and relationship expert Dr. Yvonne Kristin Fulbright’s guide will prove a saviour for you.

And she says that before taking the plunge and share, you should first ask yourself the following questions:

1. What’s my motivation?

Why do you want to share this fantasy? What turns you on about sharing? Do you hope the sharing can be a form of foreplay or something more? Are you hoping that your fantasy will be fulfilled? Will it be advantageous to your relationship to share, revving up sex for the both of you?

2. Will sharing diffuse my own pleasuring?

Many lovers like to have a few tricks up their sleeves in bed, and their private fantasies are often what makes or breaks the sexual moment. Whether it’s getting through a sex act or working your way to orgasm, will sharing take away from how your fantasy benefits you now? Will you be able to enjoy having the cat out of the bag?

3. Am I in the right kind of relationship for sharing?

Not every relationship can weather such intimate sharing. You need to be in a secure, trusting relationship. Your sexual union should be able to provide you with the support and safety needed to get over any nervousness and anxiety, and to field any reactions. Lovers need to make each other feel accepted and emotionally safe. This includes being able to refuse a request to act out a fantasy without putting the other down.

4. Can my partner handle my fantasies?

Some lovers can’t handle hearing about certain sex acts, especially if they involve “who” you’re fantasizing about. Partners who are sex negative or uncomfortable with sexual intimacy in general are not going to be the best candidates for such sharing. So consider what your lover may be open to and which types of fantasies may cause more harm than good.

5. Am I ready to hear my partner’s fantasies?

Lovers tend to expect reciprocity when sharing fantasies. It’s usually not a one-way street, so you have to consider how you might react to your partner’s fantasies. Can you go there? How can you provide the same safety you’re hoping for?

After the self-questioning comes the sharing part, so think long and hard about when to open up. And don’t expose a fantasy after a hot romp, for it may not be received as well as one meant to arouse desire.

Let your partner know that you want to share something and explain your reasons for wanting to share.

Finally, remind your lover that your relationship means more than any fantasy. Your partner should not feel undesirable at all.

Animals farmed for meat main source of food poisoning bug

Tuesday, September 30th, 2008

Researchers from Lancashire, England, and Chicago, IL, have discovered that animals farmed for meat are the main source of bacteria responsible for food poisoning.

They suggested that 97 pct of the foodbourne illnesses are caused by bacteria typically found in chicken and livestock.

While studying campylobacteriosis cases, the research team found that 97 pct of the cases in Lancashire, UK, were caused by bacteria typically found in chicken and livestock.

The study was based on DNA-sequence comparison of thousands of bacteria collected from human patients and animal carriers.

The research team led by Daniel Wilson, of the University of Chicago, and formerly Lancaster University, United Kingdom, sequenced the DNA of bacteria collected from 1,231 patients and compared it to Campylobacter jejuni DNA sequences collected from wild and domestic animals, and the environment.

They used evolutionary modelling to trace the ancestry of human C jejuni back to one of seven source populations.

The team found that in 57 percent of cases, the bacteria could be traced to chicken, and in 35 percent to cattle. Wild animal and environmental sources were accountable for just three percent of disease.

“The dual observations that livestock are a frequent source of human disease isolates and that wild animals and the environment are not, strongly support the notion that preparation or consumption of infected meat and poultry is the dominant transmission route,” said Wilson.

The study appears in the open-access journal PLoS Genetics.

Meat-eating dinosaur helps unravel how birds evolved breathing system

Tuesday, September 30th, 2008

The remains of a big predatory dinosaur, discovered along Rio Colorado river banks in Argentina, is helping to unravel how birds evolved their unusual breathing system.The discovery by University of Chicago’s Paul Sereno, a National Geographic explorer-in-residence and his team, builds on decades of paleontological research indicating that birds evolved from dinosaurs.

Joining Sereno to announce the discovery at a news conference in Mendoza, Argentina on Monday were Ricardo Martinez and Oscar Alcober, both of the Universidad Nacional de San Juan, Argentina.’

‘Among land animals, birds have a unique way of breathing. The lungs actually don’t expand,’ Sereno said. Instead, birds have developed a system of bellows, or air sacs, which help pump air through the lungs. It’s the reason birds can fly higher and faster than bats, which, like all mammals, expand their lungs in a less efficient breathing process.

Discovered in 1996, the new dinosaur is named Aerosteon riocoloradensis or ‘air bones from the Rio Colorado.’ ‘Aerosteon, found in rocks dating to the Cretaceous period about 85 million years old, represents a lineage surviving in isolation in South America.

Its closest cousin in North American, Allosaurus, had gone extinct millions of years earlier and was replaced by tyrannosaurs.

The University of Chicago press release said lab technicians spent years cleaning and CT-scanning the bones, which were embedded in hard rock, to finally reveal the evidence of air sacs within Aerosteon’s body cavity

Previously, paleontologists had found only tantalising evidence in the backbone, outside the cavity with the lungs. ‘This dinosaur, unlike any other, provides more direct evidence of the bellows involved in bird breathing,’ Martinez said.

Its bones have telltale pockets and a sponge-like texture called ‘pneumatization,’ in which air sacs from the lung invade bone. Air-filled bones are the hallmark of the bellows system of breathing in birds.

Alcober noted: ‘Despite its huge body size and lack of a breastbone or birdlike ribcage, this meat-eater had lungs that already functioned quite a bit like a bird’s.’

Said co-author of the study Jeffrey Wilson University of Michigan: ‘The ancient history of features like air sacs is full of surprising turns, the explanations for which must account for their presence in a huge predator like Aerosteon as well as in a chicken.’

These findings were published on Monday in the online version of the Public Library of Science ONE.

Huge web traffic may crash online ’spider phobia’ survey site

Tuesday, September 30th, 2008

Aussie researchers behind a website offering free online treatment for fear of spiders, scientifically know as arachnophobia, are afraid that a huge response from people may crash their site.However, the group behind the website, Feardrop, still want people to test out their treatment.

University of Tasmania psychiatry researcher Philippa Cannan, one of the persons behind the online treatment website, points out that about five per cent of the adult population experience some form of phobia, with higher rates found among females than males.

She says that many people suffer arachnophobia, some with seriously dangerous panic reactions and intrusive checking behaviour, but still few of them seek treatment.

“Some people have told us they have broken limbs trying to get away from spiders because they have been so terrified,” news.com.au quoted her as saying.

“After successful treatment they don’t have to have the same intense shock of anxiety in response,” she added.

Feardrop hope that website will help more people access treatment.

“While there are currently some online programs which provide instructions on exposure, to our knowledge, this is the first program to directly deliver exposure treatment online,” Cannan said.

“This spider phobia treatment involves people looking at images of spiders and rating their level of anxiety.

“Participants will learn to look at the pictures until their anxiety level is low.

“It is expected that the learning that occurs online will help people to reduce their fear of spiders in everyday life,” she added.

Arachnophobes respond to the research team’s anxiety questionnaire before moving on to a graded exposure exercise, in which phobics follow a small circle with their computer mouse as it travels over a number of photographic images of huntsman spiders.

The program’s organisers hope to expand the program to include snakes and dogs.

Presently, people in Hobart have been asked to participate in the trial to determine the effectiveness of the test.

Cannan, however, is worried that the response could overwhelm it.

Study links birth size and breast cancer

Tuesday, September 30th, 2008

Women who were bigger and longer babies may be more likely to develop breast cancer, researchers reported on Tuesday.

The study adds to evidence that, at least in some cases, something that happens in the womb may cause cancer later in life.

Previous research into links between birth size and breast cancer have proved inconsistent, but the findings published in the Public Library of Science journal PLoS Medicine are strong evidence that the two may be related.

“These findings provide strong evidence that birth size — in particular birth length — is a marker of a woman’s breast cancer risk in adulthood, although the mechanisms underlying this association are unclear,” Isabel dos Santos Silva of the London School of Hygiene and Tropical Medicine and colleagues wrote.

Breast cancer is the leading cause of cancer deaths among women worldwide, according to the American Cancer Society. The group estimates about 465,000 women died of breast cancer globally in 2007, and 1.3 million new cases were diagnosed.

Declining death rates from breast cancer in developed countries have been attributed to early detection through mammography screening and to improved treatment.

Dos Santos Silva and colleagues examined 32 studies comprising 600,000 women, mainly in developed countries. Their analysis included more than 22,000 women who had breast cancer.

After considering established risk factors such as age and late menopause, the researchers found a strong association with birth size, birth length and head circumference. Of the three, birth length showed the strongest link.

“The amount by which birth size affected breast cancer risk was not affected by allowing for other established risk factors,” the researchers wrote.

For example, women with recorded birth weights of 4 kilograms or more had a 12 percent higher chance of breast cancer than babies weighing 3 to 3.5 kilograms at birth, the study found.

The link between breast cancer and birth size appeared smaller when compared with other risk factors. The researchers estimated that birth size may be responsible for up to 5 percent of all women who develop breast cancer by the age of 80.

Some research has linked hormones such as estrogen and human growth hormone with cancer.

The researchers noted age of puberty and adult height are also associated with breast cancer risk, and growth as a fetus can predict a girl’s growth, so there could be a link there.

“The maternal and/or foetal hormonal environment associated with large birth size may alter programing of the breast, making it more susceptible to cancer,” the researchers wrote.

Health Tip: Does Your Child Need a Nap?

Monday, September 29th, 2008

Children need plenty of sleep to keep them healthy and happy.

Take note of these warning signs that your child may need a daily nap, courtesy of the Nemours Foundation:

  • Acting sleepy during the day.
  • Acting cranky or fussy late in the afternoon.
  • Difficulty getting out of bed in the morning.
  • Difficulty concentrating, hyperactivity, impatience or aggression.
  • Problems concentrating on school work or other tasks.

Nintendo to launch camera, music-capable DS: report

Monday, September 29th, 2008

Japanese video game maker Nintendo Co Ltd plans to launch a new model of its DS handheld machine that can take pictures and play music by the end of the year, the Nikkei business daily said on Sunday.

The move would pit the top-selling portable game gear with Apple Inc iPod and camera-embedded cellphones in general.

The price for the new machine, which will also be equipped with advanced wireless communications functions, is expected to be below 20,000 yen ($189) in Japan, compared with 16,800 yen for the current model, the Nikkei said.

The Wii game console and DS have been Nintendo’s twin growth engines, helping its share price to grow more than three-fold over the past three years.

The DS far outsells Sony Corp’s rival machine, PlayStation Portable (PSP), globally.

But in Japan, the PSP’s unit sales exceeded the DS’s in five consecutive months through July, according to game magazine publisher Enterbrain, in a potential sign of slowing momentum for the current DS model.

Nintendo officials were not immediately available for comment.

($1=105.97 Yen)

Chinese astronauts return home after landmark spacewalk

Monday, September 29th, 2008

Three Chinese astronauts, who made history after conducting the country’s first spacewalk Saturday, returned home safely in a Shenzhou-7 module that landed in China’s central Inner Mongolia region Sunday.Astronauts Zhai Zhigang, Liu Boming, and Jing Haipeng returned to earth from a 68-hour space flight that included a 20-minute spacewalk.

‘It was a glorious mission, full of challenges, but the result was perfect. I’m proud of my country,’ said Zhigang, sitting on a chair after emerging from the module.

The space capsule was suspended down by a 1,000-sq-meter parachute and landed on its flank at Siziwang Banner in central Inner Mongolia, where around 300 officials waited to conduct search and rescue.

Prime Minister Wen Jiabao, who arrived at the control centre to watch the landing, beamed with smile when the spacecraft touched ground.

The astronauts were examined by doctors and adapted themselves to the gravitation on Earth before exiting the module, the search headquarters told Xinhua.

They will be taken to a hospital in the Inner Mongolia capital Hohhot for medical examination and are scheduled to fly back to Beijing Monday.

The trio will spend around two weeks in quarantine, before meeting their family, said Zhai’s wife Zhang Shujing.

The three men were blasted off aboard a Shenzhou-7 spacecraft at 9.10 p.m. Thursday. China had sent a lone Yang Liwei in space in 2003, and sent two men on a five-day journey in 2005.

This successful spacewalk mission makes China the third to master the extra-vehicular activity (EVA) technology after the US and Russia.

During the spacewalk Saturday, Zhai wore a $4 million homemade Feitian space suit and spent 20 minutes outside the spacecraft. Tethered to the craft with two safety wires and a long electric cord providing oxygen and communications, he moved slowly along a set of handrails around the orbital module.

‘I feel well. I am here greeting the Chinese people and people of the whole world,’ Zhai said. He waved a Chinese flag handed over by his companion Liu Boming, who helped the ‘walk’ in the orbital module.

Later Zhai retrieved a test sample of solid lubricant placed outside the orbiter, as part of an experiment to test the durability of the materials.

After the spacewalk, he was congratulated by Chinese President Hu Jintao, who watched live transmission of the spacewalk from the Beijing control centre.

Hu hailed the spacewalk as a breakthrough and thanked the astronauts for their devotion and excellent work.

Other tasks of the mission included carrying out trials of satellite data relay and releasing a 40-kg companion satellite, which was left in the space with the orbital module and the extravehicular space suits.

The live telecast of the historic moment was watched by tens of millions of Chinese on outdoor screens and television sets at homes.

World mourns “king of cool” Paul Newman

Monday, September 29th, 2008

Images of U.S. actor Paul Newman, who died late on Friday, adorned newspaper front pages around the world on Sunday, his piercing blue eyes vying for attention alongside headlines of the global financial crisis.Underlining Newman’s international appeal, Britain’s Independent on Sunday featured his photograph across the whole of page one, relegating the latest news of the country’s banking woes to the inside pages.

“Paul Newman: Death of King Cool” ran the caption headline in the Sunday Times above a portrait of the heartthrob and philanthropist, who died of cancer aged 83.

The Observer weekly devoted a two-page spread under the words: “An Actor of True Genius and a Man of Great Decency”, focusing on Newman’s philanthropy and devotion to his family, as well as on his big screen roles.

In France, politicians lined up to praise Newman, with President Nicolas Sarkozy hailing him as a “Hollywood legend”.

“Actor, author, screenwriter, director, producer and philanthropist, he was also a great friend of France and fans of motor racing will remember his successive appearances at the Le Mans 24-hour race,” Sarkozy said in a statement.

“The death of a good guy,” France’s main Sunday newspaper, Le Journal du Dimanche, said in a headline, giving over most of its front page to a photo of the U.S. actor.

Even conservative Muslim Iran, which would not usually concern itself with reporting on a Western film star, marked his death. Two pro-reform newspapers displayed the actor on their front pages while Iran’s state media also reported his death.

The Etemad newspaper, published Newman’s picture, saying “Fading away the last classic star” and the Kargozaran daily said “End of the blue-eyed boy”.

In Germany as elsewhere, news television channels have been showing clips from his films.

“Paul Newman - the Last Hero is Dead” ran a headline on the back page of the mass-selling Bild am Sonntag. A strapline in the same newspaper read: “This damn cancer. Now it has killed the bluest eyes in the world!”

Several obituaries repeated comments he made about his famous good looks.

“I picture my epitaph,” he was quoted as saying. “Here lies Paul Newman, who died a failure because his eyes turned brown.”

“WHAT PAIN!” SAYS LOREN

The New York Times called him a “magnetic Hollywood titan”, and in Italy actress Sophia Loren, who appeared in the film “Lady L” with Newman, called the news “a blow”.

“When such important personalities die, one despairs and thinks that, little by little, all the greats are disappearing,” she told the Il Messaggero daily.

Israeli actor Haim Topol, who Newman helped to set up camps for children with incurable diseases, called him a “dear human being”.

“He busied himself with the professional rather than with PR,” Topol told Israel Radio. “His main motto was, ‘If you do not exploit your success in order to improve things in the world, then you are really wasting it’.”

Paul Leonard Newman, known as “PL” to friends, appeared in more than 50 movies, including “Cat on a Hot Tin Roof,” “Butch Cassidy and the Sundance Kid” and “The Sting”.

He earned nine Oscar nominations for acting and won the best actor award for 1986’s “The Color of Money.”

A director and race car driver as well as an actor, Newman was also known for his extensive philanthropy. He created Newman’s Own food products, which funnelled more than $250 million in profits to thousands of charities worldwide.

Newman said his deepest satisfaction came from philanthropy.

Particularly close to his heart were his Hole-in-the-Wall Camps for seriously ill children. Today, there are 11 around the world that have helped over 135,000 kids, all free of charge.

Newman is survived by his wife of 50 years Joanne Woodward, five daughters, two grandsons, and his older brother, Arthur. Newman also had a son Scott, who died in 1978.